The SHR as a Small Animal Model for Radiocontrast Renal Failure. Relation of Nephrotoxicity to Animal's Age, Gender, Strain, and Dose of Radiocontrast
نویسندگان
چکیده
منابع مشابه
Molecular Mechanisms of Renal Cellular Nephrotoxicity due to Radiocontrast Media
Modern iodinated radiocontrast media are all based on the triiodinated benzene ring with various chemical modifications having been made over the last few decades in order to reduce their toxicity. However, CIN remains a problem especially in patients with pre-existing renal failure. In vitro studies have demonstrated that all RCM are cytotoxic. RCM administration in vivo may lead to a decrease...
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آب حاصل از بارش منبع تأمین نیازهای بی شمار جانداران به ویژه انسان است و هرگونه کاهش در کم و کیف آن مستقیماً حیات موجودات زنده را تحت تأثیر منفی قرار می دهد. نوسان سال به سال بارش از ویژگی های اساسی و بسیار مهم بارش های سالانه ایران محسوب می شود که آثار زیان بار آن در تمام عرصه های اقتصادی، اجتماعی و حتی سیاسی- امنیتی به نحوی منعکس می شود. چون میزان آب ناشی از بارش یکی از مولفه های اصلی برنامه ...
15 صفحه اولCharacterization of a novel model for investigation of radiocontrast nephrotoxicity.
OBJECTIVES Radiocontrast agents are one of the most common causes of acute renal failure in the world. These agents are required for both diagnostic and therapeutic modalities of medical intervention, including computed tomography (CT), angiography and cardiac catheterization. Publications over the past 40 years support three potential mechanisms of toxicity: oxidative stress, haemodynamics and...
متن کاملNephrotoxicity of low osmolar radiocontrast agents in patients with chronic renal failure.
Dr. P. Cacoub, Department of Nephrology, Hôpital Pitié-Salpêtrière, 47-83, boulevard de l’Hôpital, F-75651 Paris Cédex 13 (France) Dear Sir, Acute renal failure has long been recognized as a potential hazard of radiocontrast administration, especially in patients with preexisting renal failure [1]. Recently developed low osmolar agents have been considered less nephrotoxic, but some studies ind...
متن کاملN-acetylcysteine for prevention of radiocontrast induced nephrotoxicity: the importance of dose and route of administration.
Dose and route of administration of N-acetylcysteine are key factors to consider when evaluating whether this agent is effective in preventing radiocontrast induced nephropathy.
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ژورنال
عنوان ژورنال: Renal Failure
سال: 1997
ISSN: 0886-022X,1525-6049
DOI: 10.3109/08860229709037213